Cellosaurus JHU-022 (CVCL_5991)

Cell line name JHU-022
Synonyms JHU-022-SCC; JHU022; JHU-O22; JHU-22; HNSCC 022; O22; 022
Accession CVCL_5991
Resource Identification Initiative To cite this cell line use: JHU-022 (RRID:CVCL_5991)
Comments Part of: MD Anderson Cell Lines Project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Misspelling: JUH022; In Cosmic 2131848.
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_5987 (JHU-012)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; PubMed=21868764

Markers:
AmelogeninX,Y
CSF1PO10
D13S31711
D16S53912
D5S81812,13
D7S8209,10
TH016
TPOX8
vWA14,16
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=12925955; DOI=10.1002/ijc.11341
Minhas K.M., Singh B., Jiang W.W., Sidransky D., Califano J.A.
Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma.
Int. J. Cancer 107:46-52(2003)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections ATCC; CRL-2722 - Discontinued
Cell line databases/resources Cosmic-CLP; 1240162
GDSC; 1240162
Ontologies BTO; BTO:0003887
Gene expression databases GEO; GSM1669959
Polymorphism and mutation databases Cosmic; 1122671
Cosmic; 1530748
Cosmic; 2131848