ID   KY-Rb
AC   CVCL_5A05
DR   cancercelllines; CVCL_5A05
DR   Wikidata; Q54900772
RX   CelloPub=CLPUB00209;
CC   Population: Japanese.
CC   Selected for resistance to: ChEBI; CHEBI:28680; Cytarabine (Arabinosylcytosine; Ara-C).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000375871; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Brain, meninges; UBERON=UBERON_0010743.
DI   NCIt; C7463; Acute myelomonocytic leukemia
DI   ORDO; Orphanet_517; Acute myelomonocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1346 ! KY821
SX   Male
AG   28Y
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 05-10-23; Version: 12
//
RX   CelloPub=CLPUB00209;
RA   Kakihara T.;
RT   "The characterization of highly resistant human leukemic cell lines to
RT   1-beta-D-arabinofuranosylcytosine.";
RL   Acta Med. Biol. 39:119-127(1991).
//