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Cellosaurus K177 (CVCL_5I63)

[Text version]

Cell line name K177
Synonyms K-177
Accession CVCL_5I63
Resource Identification Initiative To cite this cell line use: K177 (RRID:CVCL_5I63)
Comments Transfected with: HGNC; 1958; CHRNA4.
Transfected with: HGNC; 1962; CHRNB2.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line

Gopalakrishnan M., Monteggia L.M., Anderson D.J., Molinari E.J., Piattoni-Kaplan M., Donnelly-Roberts D., Arneric S.P., Sullivan J.P.
Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.
J. Pharmacol. Exp. Ther. 276:289-297(1996)

PubMed=11245666; DOI=10.1523/JNEUROSCI.21-06-01819.2001
Buisson B., Bertrand D.
Chronic exposure to nicotine upregulates the human (alpha)4((beta)2 nicotinic acetylcholine receptor function.
J. Neurosci. 21:1819-1829(2001)

Chemistry resources ChEMBL-Cells; CHEMBL3308619
ChEMBL-Targets; CHEMBL614687
Other Wikidata; Q54899263
Entry history
Entry creation14-Dec-2015
Last entry update07-Sep-2018
Version number5