ID   K177
AC   CVCL_5I63
SY   K-177
DR   ChEMBL-Cells; CHEMBL3308619
DR   ChEMBL-Targets; CHEMBL614687
DR   Wikidata; Q54899263
RX   PubMed=8558445;
RX   PubMed=11245666;
CC   Transfected with: HGNC; 1958; CHRNA4.
CC   Transfected with: HGNC; 1962; CHRNB2.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 14-12-15; Last updated: 07-09-18; Version: 5
//
RX   PubMed=8558445;
RA   Gopalakrishnan M., Monteggia L.M., Anderson D.J., Molinari E.J.,
RA   Piattoni-Kaplan M., Donnelly-Roberts D., Arneric S.P., Sullivan J.P.;
RT   "Stable expression, pharmacologic properties and regulation of the
RT   human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.";
RL   J. Pharmacol. Exp. Ther. 276:289-297(1996).
//
RX   PubMed=11245666; DOI=10.1523/JNEUROSCI.21-06-01819.2001;
RA   Buisson B., Bertrand D.;
RT   "Chronic exposure to nicotine upregulates the human (alpha)4((beta)2
RT   nicotinic acetylcholine receptor function.";
RL   J. Neurosci. 21:1819-1829(2001).
//