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Cellosaurus U-87 MG-luc2 (CVCL_5J15)

[Text version]
Cell line name U-87 MG-luc2
Synonyms U87MG-luc2
Accession CVCL_5J15
Resource Identification Initiative To cite this cell line use: U-87 MG-luc2 (RRID:CVCL_5J15)
Comments Problematic cell line: Misidentified. Parent cell line (U-87MG ATCC) is not the original glioblastoma cell line established in 1968 at the University of Uppsala.
Population: Caucasian.
Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Sequence variations
  • Mutation; HGNC; 7765; NF1; Simple; p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT); ClinVar=VCV000420078; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; c.209+1G>T; ClinVar=VCV000229705; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0022 (U-87MG ATCC)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Cross-references
Cell line collections (Providers) PerkinElmer; 124577 - Discontinued
Cell line databases/resources cancercelllines; CVCL_5J15
Encyclopedic resources Wikidata; Q54973601
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number13