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Cellosaurus LNCaP-luc-M6 (CVCL_5J30)

[Text version]

Cell line name LNCaP-luc-M6
Accession CVCL_5J30
Resource Identification Initiative To cite this cell line use: LNCaP-luc-M6 (RRID:CVCL_5J30)
Comments Population: Caucasian.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Sequence variations
  • Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Left supraclavicular lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1379 (LNCaP clone FGC)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=15042605; DOI=10.1002/pros.20003
Scatena C.D., Hepner M.A., Oei Y.A., Dusich J.M., Yu S.-F., Purchio T., Contag P.R., Jenkins D.E.
Imaging of bioluminescent LNCaP-luc-M6 tumors: a new animal model for the study of metastatic human prostate cancer.
Prostate 59:292-303(2004)

Cross-references
Cell line collections PerkinElmer; 119271 - Discontinued
Encyclopedic resources Wikidata; Q54902842
Entry history
Entry creation14-Dec-2015
Last entry update23-Jun-2022
Version number9