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Cellosaurus Walvax-2 (CVCL_5J50)

[Text version]

Cell line name Walvax-2
Synonyms WALVAX-2; WALVAX 2; Walvax 2; WALVAX2
Accession CVCL_5J50
Resource Identification Initiative To cite this cell line use: Walvax-2 (RRID:CVCL_5J50)
Comments Group: Vaccine production cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection (CCTCC); C201055.
Characteristics: Maintains excellent capabilities for growth and proliferation until PDL 50 (max PDL is 58).
Doubling time: 39-41 hours (at 28th passage), 40-42 hours (at 38th passage), 57-62 hours (at 48th passage) (PubMed=25803132).
Anecdotal: Is causing an outrage in some pro-lifer circles because it is a cell line originating from an aborted (for medical reasons) 3-month old female fetus.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 3FM
Category Finite cell line
STR profile Source(s): PubMed=25803132

Markers:
AmelogeninX
CSF1PO10,12
D3S135815,16
D5S81810,11
D7S8208,12
D8S117913,15
D13S31711,12
D16S5399,12
D18S5115,18
D21S1129,30
FGA21,24
Penta D10,11
Penta E5,18
TH016,9
TPOX8,11
vWA18

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Publications

Patent=CN103525770A
Ma B., Yang Z., He L.-F., Wang L.-L., Chen M., Wang X.
Application of human fetal lung fibroblast line in preparation of hepatitis A vaccines.
Patent number CN103525770A, 22-Jan-2014

PubMed=25803132; DOI=10.1080/21645515.2015.1009811
Ma B., He L.-F., Zhang Y.-L., Chen M., Wang L.-L., Yang H.-W., Yan T., Sun M.-X., Zheng C.-Y.
Characteristics and viral propagation properties of a new human diploid cell line, Walvax-2, and its suitability as a candidate cell substrate for vaccine production.
Hum. Vaccin. Immunother. 11:998-1009(2015)

Cross-references
Other Wikidata; Q54993580