Cellosaurus MDA-MB-435s-mKate2 (CVCL_5T70)

Cell line name MDA-MB-435s-mKate2
Accession CVCL_5T70
Resource Identification Initiative To cite this cell line use: MDA-MB-435s-mKate2 (RRID:CVCL_5T70)
Comments Problematic cell line: Contaminated. Grand-parent cell line (MDA-MB-435) has been shown to be a M14 derivative.
Sequence variation: Heterozygous for BRAF p.Val600Glu (from parent cell line).
Sequence variation: Heterozygous for TP53 p.Gly266Glu (from parent cell line).
Transfected with: mKate2; a bright red fluorescent protein derived from eqFP578.
Disease Amelanotic melanoma (NCIt: C3802)
Derived from metastatic site: Subcutaneous; right buttock.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0622 (MDA-MB-435S)
Sex of cell Male
Category Cancer cell line

PubMed=25902968; DOI=10.1007/s11307-015-0853-5
Vuletic I., Liu J.-H., Wu H.-L., Ding Y.-C., Lei Y., Li C.-H., Zhu D.-H., Ren Q.-S., Sun H.-F., Li J.
Establishment of an mKate2-expressing cell line for non-invasive real-time breast cancer in vivo imaging.
Mol. Imaging Biol. 17:811-818(2015)