Cellosaurus cell line MDA-MB-231/B02 (CVCL

Cellosaurus MDA-MB-231/B02 (CVCL_5T76)

[Text version]

Cell line name

MDA-MB-231/B02

Synonyms

MDA-MB-231-B02; MDA-B02; B02

Accession

CVCL_5T76

Resource Identification Initiative

To cite this cell line use: MDA-MB-231/B02 (RRID:CVCL_5T76)

Comments

Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Omics: Proteomics; Subcellular; Cell surface.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line).

Disease

Breast adenocarcinoma (NCIt: C5214)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0062 (MDA-MB-231)
Children:

CVCL_5T77 (B02/GFP.2)

Sex of cell

Female

Age at sampling

51Y