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Cellosaurus MDA-MB-231/B02 (CVCL_5T76)

[Text version]

Cell line name MDA-MB-231/B02
Synonyms MDA-MB-231-B02; MDA-B02; B02
Accession CVCL_5T76
Resource Identification Initiative To cite this cell line use: MDA-MB-231/B02 (RRID:CVCL_5T76)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Omics: Cell surface proteome.
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0062 (MDA-MB-231)
Children:
CVCL_5T77 (B02/GFP.2)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=11697798; DOI=10.1359/jbmr.2001.16.11.2027
Peyruchaud O., Winding B., Pecheur I., Serre C.-M., Delmas P., Clezardin P.
Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions.
J. Bone Miner. Res. 16:2027-2034(2001)

PubMed=18714363; DOI=10.1593/neo.08570
Kischel P., Guillonneau F., Dumont B., Bellahcene A., Stresing V., Clezardin P., De Pauw E.A., Castronovo V.
Cell membrane proteomic analysis identifies proteins differentially expressed in osteotropic human breast cancer cells.
Neoplasia 10:1014-1020(2008)

Cross-references
Ontologies BTO; BTO:0004955
Other Wikidata; Q54904613
Entry history
Entry creation23-Feb-2016
Last entry update02-Jul-2020
Version number11