ID   MDA-MB-231/B02
AC   CVCL_5T76
SY   MDA-MB-231-B02; MDA-B02; B02
DR   BTO; BTO:0004955
DR   Wikidata; Q54904613
RX   PubMed=11697798;
RX   PubMed=18714363;
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Sequence variation: Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
CC   Sequence variation: Homozygous for CDKN2A deletion (from parent cell line).
CC   Sequence variation: Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
CC   Sequence variation: TERT c.228C>T (-124C>T); in promoter (from parent cell line).
CC   Sequence variation: Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
CC   Omics: Cell surface proteome.
CC   Derived from metastatic site: Pleural effusion.
DI   NCIt; C5214; Breast adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0062 ! MDA-MB-231
SX   Female
AG   51Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 02-07-20; Version: 11
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RX   PubMed=11697798; DOI=10.1359/jbmr.2001.16.11.2027;
RA   Peyruchaud O., Winding B., Pecheur I., Serre C.-M., Delmas P.,
RA   Clezardin P.;
RT   "Early detection of bone metastases in a murine model using
RT   fluorescent human breast cancer cells: application to the use of the
RT   bisphosphonate zoledronic acid in the treatment of osteolytic
RT   lesions.";
RL   J. Bone Miner. Res. 16:2027-2034(2001).
//
RX   PubMed=18714363; DOI=10.1593/neo.08570;
RA   Kischel P., Guillonneau F., Dumont B., Bellahcene A., Stresing V.,
RA   Clezardin P., De Pauw E.A., Castronovo V.;
RT   "Cell membrane proteomic analysis identifies proteins differentially
RT   expressed in osteotropic human breast cancer cells.";
RL   Neoplasia 10:1014-1020(2008).
//