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Cellosaurus B02/GFP.2 (CVCL_5T77)

[Text version]

Cell line name B02/GFP.2
Accession CVCL_5T77
Resource Identification Initiative To cite this cell line use: B02/GFP.2 (RRID:CVCL_5T77)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Transfected with: UniProtKB; P42212; GFP.
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5T76 (MDA-MB-231/B02)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=11697798; DOI=10.1359/jbmr.2001.16.11.2027
Peyruchaud O., Winding B., Pecheur I., Serre C.-M., Delmas P., Clezardin P.
Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions.
J. Bone Miner. Res. 16:2027-2034(2001)

Cross-references
Other Wikidata; Q54752256
Entry history
Entry creation23-Feb-2016
Last entry update02-Jul-2020
Version number9