ID   B02/GFP.2
AC   CVCL_5T77
DR   cancercelllines; CVCL_5T77
DR   Wikidata; Q54752256
RX   PubMed=11697798;
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P42212; GFP.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C5214; Breast adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_5T76 ! MDA-MB-231/B02
SX   Female
AG   51Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 05-10-23; Version: 17
//
RX   PubMed=11697798; DOI=10.1359/jbmr.2001.16.11.2027;
RA   Peyruchaud O., Winding B., Pecheur I., Serre C.-M., Delmas P.,
RA   Clezardin P.;
RT   "Early detection of bone metastases in a murine model using
RT   fluorescent human breast cancer cells: application to the use of the
RT   bisphosphonate zoledronic acid in the treatment of osteolytic
RT   lesions.";
RL   J. Bone Miner. Res. 16:2027-2034(2001).
//