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Cellosaurus RCC10 (CVCL_6265)

[Text version]
Cell line name RCC10
Synonyms RCC-10
Accession CVCL_6265
Resource Identification Initiative To cite this cell line use: RCC10 (RRID:CVCL_6265)
Comments From: Bauer C., University of Zurich; Zurich; Switzerland.
Sequence variations
  • Mutation; HGNC; 12687; VHL; Simple; p.Lys159fs (c.474_477del); Zygosity=Unspecified (PubMed=11114720).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_6266 (RCC63)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=11114720; DOI=10.1038/sj.onc.1203938
Krieg M., Haas R., Brauch H., Acker T., Flamme I., Plate K.H.
Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Oncogene 19:5435-5443(2000)

PubMed=15985433; DOI=10.1074/jbc.M500971200
Alberghini A., Recalcati S., Tacchini L., Santambrogio P., Campanella A., Cairo G.
Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells.
J. Biol. Chem. 280:30120-30128(2005)

Cross-references
Anatomy/cell type resources BTO; BTO:0004932
Encyclopedic resources Wikidata; Q54949451
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number9