Cellosaurus cell line RCC63 (CVCL_6266)

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Cell line name	RCC63
Synonyms	RCC10wt63
Accession	CVCL_6266
Resource Identification Initiative	To cite this cell line use: RCC63 (RRID:CVCL_6266)
Comments	Transfected with: HGNC; 12687; VHL. Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Sequence variations	Mutation; HGNC; 12687; VHL; Simple; p.Lys159fs (c.474_477del); Zygosity=Unspecified (PubMed=11114720).
Disease	Clear cell renal cell carcinoma (NCIt: C4033) Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_6265 (RCC10)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=11114720; DOI=10.1038/sj.onc.1203938 Krieg M., Haas R., Brauch H., Acker T., Flamme I., Plate K.H. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Oncogene 19:5435-5443(2000) PubMed=15985433; DOI=10.1074/jbc.M500971200 Alberghini A., Recalcati S., Tacchini L., Santambrogio P., Campanella A., Cairo G. Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells. J. Biol. Chem. 280:30120-30128(2005)
Encyclopedic resources	Wikidata; Q54949470
Entry history
Entry creation	04-Apr-2012
Last entry update	05-Oct-2023
Version number	9