ID   RCC63
AC   CVCL_6266
SY   RCC10wt63
DR   Wikidata; Q54949470
RX   PubMed=11114720;
RX   PubMed=15985433;
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; p.Lys159fs (c.474_477del); Zygosity=Unspecified (PubMed=11114720).
CC   Transfected with: HGNC; 12687; VHL.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_6265 ! RCC10
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 9
//
RX   PubMed=11114720; DOI=10.1038/sj.onc.1203938;
RA   Krieg M., Haas R., Brauch H., Acker T., Flamme I., Plate K.H.;
RT   "Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha
RT   under normoxic conditions in renal carcinoma cells by von
RT   Hippel-Lindau tumor suppressor gene loss of function.";
RL   Oncogene 19:5435-5443(2000).
//
RX   PubMed=15985433; DOI=10.1074/jbc.M500971200;
RA   Alberghini A., Recalcati S., Tacchini L., Santambrogio P.,
RA   Campanella A., Cairo G.;
RT   "Loss of the von Hippel Lindau tumor suppressor disrupts iron
RT   homeostasis in renal carcinoma cells.";
RL   J. Biol. Chem. 280:30120-30128(2005).
//