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Cellosaurus ScN2a (CVCL_6268)

[Text version]
Cell line name ScN2a
Accession CVCL_6268
Resource Identification Initiative To cite this cell line use: ScN2a (RRID:CVCL_6268)
Comments Characteristics: Infected with mouse RML strain prions.
Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010.
Cell type: Neural crest derived neuroblast; CL=CL_0002676.
Disease Mouse neuroblastoma (NCIt: C21993)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: A/J.
Hierarchy Parent: CVCL_0470 (Neuro-2a)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=10756052; DOI=10.1128/JVI.74.9.4377-4386.2000
Bosque P.J., Prusiner S.B.
Cultured cell sublines highly susceptible to prion infection.
J. Virol. 74:4377-4386(2000)

PubMed=17850126; DOI=10.1021/jm070688r
Kimata A., Nakagawa H., Ohyama R., Fukuuchi T., Ohta S., Doh-ura K., Suzuki T., Miyata N.
New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation.
J. Med. Chem. 50:5053-5056(2007)

Cross-references
Anatomy/cell type resources BTO; BTO:0003716
Chemistry resources ChEMBL-Cells; CHEMBL3308084
ChEMBL-Targets; CHEMBL613872
PubChem_Cell_line; CVCL_6268
Encyclopedic resources Wikidata; Q54952480
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number12