Cellosaurus K2 [Human thyroid carcinoma] (CVCL_6308)

Cell line name K2 [Human thyroid carcinoma]
Accession CVCL_6308
Resource Identification Initiative To cite this cell line use: K2 [Human thyroid carcinoma] (RRID:CVCL_6308)
Comments Problematic cell line: Contaminated. Shown to be a GLAG-66 derivative (PubMed=20143388).
Disease Thyroid gland papillary carcinoma (NCIt: C4035)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9918 (GLAG-66)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=18713817; PubMed=21868764

Markers:
AmelogeninX,Y
CSF1PO11,12
D13S31711,14
D16S53911,12
D18S5118
D21S1130,31.2
D3S135818
D5S81810,11
D7S82011
D8S117915
FGA21,24
TH016,9
TPOX8
vWA17,18
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=9054892; DOI=10.1016/S0360-3016(96)00449-X
Challeton C., Branea F., Schlumberger M., Gaillard N., de Vathaire F., Badie C., Antonini P., Parmentier C.
Characterization and radiosensitivity at high or low dose rate of four cell lines derived from human thyroid tumors.
Int. J. Radiat. Oncol. Biol. Phys. 37:163-169(1997)

PubMed=10646882; DOI=10.1054/bjoc.1999.0920
Bounacer A., Schlumberger M., Wicker R., du Villard J.A., Caillou B., Sarasin A., Suarez H.G.
Search for NTRK1 proto-oncogene rearrangements in human thyroid tumours originated after therapeutic radiation.
Br. J. Cancer 82:308-314(2000)

PubMed=18713817; DOI=10.1210/jc.2008-1102
Schweppe R.E., Klopper J.P., Korch C., Pugazhenthi U., Benezra M., Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A., Smallridge R.C., Haugen B.R.
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Biological sample resources BioSample; SAMN03151644
Polymorphism and mutation databases Cosmic; 928834
Cosmic; 1162846
Cosmic; 1789443