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Cellosaurus B-3 (CVCL_6367)

[Text version]

Cell line name B-3
Synonyms HLE-B3; HLE B-3; HLEB-3; HLEB3; HLEC-B3
Accession CVCL_6367
Secondary accession CVCL_8482
Resource Identification Initiative To cite this cell line use: B-3 (RRID:CVCL_6367)
Comments Group: Patented cell line.
Problematic cell line: Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11421.
Transformant: Ad12-SV40.
Derived from sampling site: Eye; ocular lens; epithelium. Cell type=Epithelial cell.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 5-12M
Category Transformed cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO11
D5S8189,11
D7S82011
D13S31711
D16S53911,12
TH019.3
TPOX8
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=8206728
Andley U.P., Rhim J.S., Chylack L.T. Jr., Fleming T.P.
Propagation and immortalization of human lens epithelial cells in culture.
Invest. Ophthalmol. Vis. Sci. 35:3094-3102(1994)

Patent=US5643782
Andley U.P., Fleming T.P.
Immortalized epithelial cell lines.
Patent number US5643782, 01-Jul-1997

PubMed=14578405; DOI=10.1167/iovs.03-0556
Wang-Su S.-T., McCormack A.L., Yang S., Hosler M.R., Mixon A., Riviere M.A., Wilmarth P.A., Andley U.P., Garland D., Li H., David L.L., Wagner B.J.
Proteome analysis of lens epithelia, fibers, and the HLE B-3 cell line.
Invest. Ophthalmol. Vis. Sci. 44:4829-4836(2003)

Cross-references
Cell line collections ATCC; CRL-11421
Cell line databases/resources CLO; CLO_0001812
Anatomy/cell type resources BTO; BTO:0002221
Biological sample resources BioSample; SAMN03471336
Encyclopedic resources Wikidata; Q54752060
Entry history
Entry creation04-Apr-2012
Last entry update17-Mar-2022
Version number16