Cell line name | P116 | ||||||||||||||||||
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Accession | CVCL_6429 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: P116 (RRID:CVCL_6429) | ||||||||||||||||||
Comments | Omics: SNP array analysis. Derived from sampling site: Peripheral blood. | ||||||||||||||||||
Sequence variations | Heterozygous for BAX p.Glu41Argfs*19 (c.121delG) (ClinVar=VCV000009512) (from parent cell line).Heterozygous for BAX p.Glu41Glyfs*33 (c.121dupG) (ClinVar=VCV000009511) (from parent cell line).Heterozygous for FBXW7 p.Arg505Cys (c.1513C>T) (ClinVar=VCV000069961) (from parent cell line).Heterozygous for INPP5D p.Gln345Ter (c.1033C>T) (from parent cell line).Heterozygous for INPP5D c.1097+1065_1097+1112del47 (from parent cell line).Homozygous for MSH2 p.Arg711Ter (c.2131C>T) (ClinVar=VCV000090903) (from parent cell line).Homozygous for MSH6 p.Phe1088Serfs*2 (c.3261delC) (ClinVar=VCV000089363) (from parent cell line).Heterozygous for SYK p.Met34Hisfs*3 (c.98_99insG) (from parent cell line).Heterozygous for TP53 p.Arg196Ter (c.586C>T) (ClinVar=VCV000043589) (from parent cell line). | ||||||||||||||||||
Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Parent: CVCL_0367 (Jurkat E6.1) Children:
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Sex of cell | Male | ||||||||||||||||||
Age at sampling | 14Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): ATCC Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=9488454; DOI=10.1128/MCB.18.3.1388 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | ATCC; CRL-2676 | ||||||||||||||||||
Cell line databases/resources | TOKU-E; 2820 | ||||||||||||||||||
Ontologies | CLO; CLO_0008292 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03471760 | ||||||||||||||||||
Chemistry resources | GDSC; 1330986
PharmacoDB; P116_1229_2019 | ||||||||||||||||||
Gene expression databases | GEO; GSM827152 | ||||||||||||||||||
Other | Wikidata; Q54937222 | ||||||||||||||||||
Polymorphism and mutation databases | Progenetix; CVCL_6429 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 12-Jan-2021 | ||||||||||||||||||
Version number | 21 |