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Cellosaurus SC (CVCL_6444)

[Text version]

Cell line name SC
Synonyms 28SC
Accession CVCL_6444
Resource Identification Initiative To cite this cell line use: SC (RRID:CVCL_6444)
Comments Problematic cell line: Contaminated. From its STR profile it seems to be a U-937 derivative.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00525.
Derived from sampling site: Pleural effusion.
Sequence variations PICALM-MLLT10 (CALM-AF10) gene fusion (from parent cell line).
Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line).
Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59); splice donor mutation (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Children:
CVCL_EP74 (28SC-ES)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10,12
D5S81810,12
D7S8209,11
D13S31710,12
D16S53912
TH016,9.3
TPOX8,11
vWA15

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
Publications

Patent=US5447861
Collins G.W., Largen M.T.
Continuous mammalian cell lines having monocyte/macrophage characteristics and their establishment in vitro.
Patent number US5447861, 05-Sep-1995

Cross-references
Cell line collections ATCC; CRL-9855
Cell line databases/resources CLDB; cl4260
Ontologies CLO; CLO_0008954
Other Wikidata; Q54952220
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number11