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Cellosaurus BG1 (CVCL_6570)

[Text version]

Cell line name BG1
Synonyms BG-1; BG-I; Bowman Gray-1; BG-1 FR
Accession CVCL_6570
Resource Identification Initiative To cite this cell line use: BG1 (RRID:CVCL_6570)
Comments Problematic cell line: Partially contaminated. Some stocks are contaminated by MCF-7 (PubMed=22710073; PubMed=25321415).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00456.
Omics: Transcriptome analysis.
Disease Ovarian adenocarcinoma (NCIt: C7700)
Adenocarcinoma of ovary (ORDO: Orphanet_213504)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_6571 (BG1Luc4E2)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=25321415

Markers:
AmelogeninX
CSF1PO10,11
D2S133822,23
D3S135816,17
D5S81812
D7S82012
D8S117912,13
D13S31710
D16S5399,11
D18S5112,15
D19S43313,15
D21S1129,33.2
TH018,9.3
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
Publications

PubMed=2910432; DOI=10.1002/1097-0142(19890115)63:2<280::AID-CNCR2820630213>3.0.CO;2-N
Geisinger K.R., Kute T.E., Pettenati M.J., Welander C.E., Dennard Y., Collins L.A., Berens M.E.
Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors.
Cancer 63:280-288(1989)

PubMed=9698466; DOI=10.1006/gyno.1998.5039
Maxwell G.L., Risinger J.I., Tong B., Shaw H., Barrett J.C., Berchuck A., Futreal P.A.
Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.
Gynecol. Oncol. 70:13-16(1998)

PubMed=9769151; DOI=10.1007/s11626-996-0015-9
Baldwin W.S., Curtis S.W., Cauthen C.A., Risinger J.I., Korach K.S., Barrett J.C.
BG-1 ovarian cell line: an alternative model for examining estrogen-dependent growth in vitro.
In Vitro Cell. Dev. Biol. Anim. 34:649-654(1998)

PubMed=22328975; DOI=10.1158/2159-8290.CD-11-0170
Hanrahan A.J., Schultz N., Westfal M.L., Sakr R.A., Giri D.D., Scarperi S., Janakiraman M., Olvera N., Stevens E.V., She Q.-B., Aghajanian C., King T.A., de Stanchina E., Spriggs D.R., Heguy A., Taylor B.S., Sander C., Rosen N., Levine D.A., Solit D.B.
Genomic complexity and AKT dependence in serous ovarian cancer.
Cancer Discov. 2:56-67(2012)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=25321415; DOI=10.1210/me.2014-1229
Li Y., Arao Y., Hall J.M., Burkett S., Liu L., Gerrish K., Cavailles V., Korach K.S.
Research resource: STR DNA profile and gene expression comparisons of human BG-1 cells and a BG-1/MCF-7 clonal variant.
Mol. Endocrinol. 28:2072-2081(2014)

Cross-references
Ontologies BTO; BTO:0000177
Biological sample resources BioSample; SAMN03151838
Chemistry resources ChEMBL-Cells; CHEMBL3307815
ChEMBL-Targets; CHEMBL613537
Gene expression databases GEO; GSM851910
Other Wikidata; Q54796229
Polymorphism and mutation databases Cosmic; 844351
Cosmic; 1709248
Entry history
Entry creation04-Apr-2012
Last entry updated02-Jul-2020
Version number17