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Cellosaurus BJ1-hTERT (CVCL_6573)

[Text version]

Cell line name BJ1-hTERT
Synonyms hTERT-BJ1; HTERT-BJ1; hTERT-BJ; hTERT BJ; BJ hTERT; BJ1; BJ-1; BJ-5ta; BJ-tert; BJhTERT; BJHTERT
Accession CVCL_6573
Secondary accession CVCL_3654
Resource Identification Initiative To cite this cell line use: BJ1-hTERT (RRID:CVCL_6573)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 36 hours (PubMed=25984343).
Transfected with: HGNC; 11730; TERT.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.29
Native American0.6
East Asian, North1.01
East Asian, South0
South Asian0.05
European, North73.33
European, South24.72
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3653 (BJ [Human fibroblast])
Sex of cell Male
Age at sampling <1M
Category Telomerase immortalized cell line
STR profile Source(s): ATCC; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135814,16
D5S81812
D7S82011,12
D8S11799,11
D13S3178,9
D16S5399,13
D18S5117,19
D21S1129
FGA22,23
Penta D12,13
Penta E7,17
TH017,8
TPOX10,11
vWA16,18

Run an STR similarity search on this cell line
Web pages http://genome.ucsc.edu/ENCODE/protocols/cell/human/BJ-5ta_Struhl_protocol.pdf
http://www.immanis.com/TelomeraseImmortalizedCellLineCulturingGuide.pdf
https://www.atcc.org/support/faqs/8f5f9/Number%20of%20population%20doublings%20PDL%20for%20ATCC%20CRL4001-475.aspx
Publications

PubMed=9454332; DOI=10.1126/science.279.5349.349
Bodnar A.G., Ouellette M.M., Frolkis M., Holt S.E., Chiu C.-P., Morin G.B., Harley C.B., Shay J.W., Lichtsteiner S., Wright W.E.
Extension of life-span by introduction of telomerase into normal human cells.
Science 279:349-352(1998)

PubMed=24119401; DOI=10.1016/j.molcel.2013.09.009
Chen J.-Y., Lin J.-R., Tsai F.-C., Meyer T.
Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle.
Mol. Cell 52:87-100(2013)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections ATCC; CRL-4001
Cell line databases/resources CCLE; BJHTERT_SKIN
DepMap; ACH-001018
Ontologies CLO; CLO_0001981
Biological sample resources BioSample; SAMN03472773
Chemistry resources PharmacoDB; BJhTERT_101_2019
Other Wikidata; Q54796970
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number20