ID   BJ1-hTERT
AC   CVCL_6573
AS   CVCL_3654
SY   hTERT-BJ1; HTERT-BJ1; hTERT-BJ; hTERT BJ; BJ hTERT; BJ1; BJ-1; BJ-5ta; BJ-tert; BJhTERT; BJHTERT
DR   ATCC; CRL-4001
DR   CLO; CLO_0001981
DR   BioSample; SAMN03472773
DR   CCLE; BJHTERT_SKIN
DR   DepMap; ACH-001018
DR   PharmacoDB; BJhTERT_101_2019
DR   Wikidata; Q54796970
RX   PubMed=9454332;
RX   PubMed=24119401;
RX   PubMed=25984343;
RX   PubMed=30894373;
RX   PubMed=31068700;
WW   http://genome.ucsc.edu/ENCODE/protocols/cell/human/BJ-5ta_Struhl_protocol.pdf
WW   http://www.immanis.com/TelomeraseImmortalizedCellLineCulturingGuide.pdf
WW   https://www.atcc.org/support/faqs/8f5f9/Number%20of%20population%20doublings%20PDL%20for%20ATCC%20CRL4001-475.aspx
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Doubling time: 36 hours (PubMed=25984343).
CC   Transfected with: HGNC; 11730; TERT.
CC   Genome ancestry: African=0.29%; Native American=0.6%; East Asian, North=1.01%; East Asian, South=0%; South Asian=0.05%; European, North=73.33%; European, South=24.72% (PubMed=30894373).
ST   Source(s): ATCC; PubMed=25877200
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 8,9
ST   D16S539: 9,13
ST   D18S51: 17,19
ST   D21S11: 29
ST   D3S1358: 14,16
ST   D5S818: 12
ST   D7S820: 11,12
ST   D8S1179: 9,11
ST   FGA: 22,23
ST   Penta D: 12,13
ST   Penta E: 7,17
ST   TH01: 7,8
ST   TPOX: 10,11
ST   vWA: 16,18
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_3653 ! BJ [Human fibroblast]
SX   Male
AG   <1M
CA   Telomerase immortalized cell line
DT   Created: 04-04-12; Last updated: 06-09-19; Version: 20
//
RX   PubMed=9454332; DOI=10.1126/science.279.5349.349;
RA   Bodnar A.G., Ouellette M.M., Frolkis M., Holt S.E., Chiu C.-P.,
RA   Morin G.B., Harley C.B., Shay J.W., Lichtsteiner S., Wright W.E.;
RT   "Extension of life-span by introduction of telomerase into normal
RT   human cells.";
RL   Science 279:349-352(1998).
//
RX   PubMed=24119401; DOI=10.1016/j.molcel.2013.09.009;
RA   Chen J.-Y., Lin J.-R., Tsai F.-C., Meyer T.;
RT   "Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to
RT   control the decision to enter the cell cycle.";
RL   Mol. Cell 52:87-100(2013).
//
RX   PubMed=25984343; DOI=10.1038/sdata.2014.35;
RA   Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S.,
RA   East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H.,
RA   Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M.,
RA   Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S.,
RA   Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D.,
RA   Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C.,
RA   Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P.,
RA   Golub T.R., Root D.E., Hahn W.C.;
RT   "Parallel genome-scale loss of function screens in 216 cancer cell
RT   lines for the identification of context-specific genetic
RT   dependencies.";
RL   Sci. Data 1:140035-140035(2014).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//