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Cellosaurus DM331 (CVCL_6626)

[Text version]

Cell line name DM331
Synonyms Duke Melanoma 331
Accession CVCL_6626
Resource Identification Initiative To cite this cell line use: DM331 (RRID:CVCL_6626)
Comments From: Duke University Medical Center; Durham; USA.
Omics: Deep exome analysis.
Omics: Transcriptome analysis.
Sequence variations Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=26405815).
HLA typing Source: PubMed=10752474
Class I
Disease Melanoma (NCIt: C3224)
Derived from metastatic site: Right axillary lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line

PubMed=10752474; DOI=10.1007/s002620050015
Slingluff C.L. Jr., Colella T.A., Thompson L., Graham D.D., Skipper J.C.A., Caldwell J., Brinckerhoff L., Kittlesen D.J., Deacon D.H., Oei C., Harthun N.L., Huczko E.L., Hunt D.F., Darrow T.L., Engelhard V.H.
Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens.
Cancer Immunol. Immunother. 48:661-672(2000)

PubMed=14871852; DOI=10.1158/0008-5472.can-03-2209
Hogan K.T., Coppola M.A., Gatlin C.L., Thompson L.W., Shabanowitz J., Hunt D.F., Engelhard V.H., Ross M.M., Slingluff C.L. Jr.
Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma.
Cancer Res. 64:1157-1163(2004)

PubMed=21654344; DOI=10.1097/CMR.0b013e328343a1d6
Molhoek K.R., Shada A.L., Smolkin M., Chowbina S., Papin J., Brautigan D.L., Slingluff C.L. Jr.
Comprehensive analysis of receptor tyrosine kinase activation in human melanomas reveals autocrine signaling through IGF-1R.
Melanoma Res. 21:274-284(2011)

PubMed=26405815; DOI=10.1371/journal.pone.0138210
Capaldo B.J., Roller D., Axelrod M.J., Koeppel A.F., Petricoin E.F. III, Slingluff C.L. Jr., Weber M.J., Mackey A.J., Gioeli D., Bekiranov S.
Systems analysis of adaptive responses to MAP kinase pathway blockade in BRAF mutant melanoma.
PLoS ONE 10:E0138210-E0138210(2015)

PubMed=26673621; DOI=10.18632/oncotarget.6548
Roller D.G., Capaldo B.J., Bekiranov S., Mackey A.J., Conaway M.R., Petricoin E.F. III, Gioeli D., Weber M.J.
Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.
Oncotarget 7:2734-2753(2016)

Gene expression databases GEO; GSM1671956
GEO; GSM1671958
GEO; GSM1671963
GEO; GSM1671971
GEO; GSM1671973
GEO; GSM1671979
GEO; GSM1671992
GEO; GSM1671994
GEO; GSM1671999
GEO; GSM1672010
GEO; GSM1672028
GEO; GSM1672031
GEO; GSM1672033
GEO; GSM1672034
GEO; GSM1672037
GEO; GSM1672052
GEO; GSM1672057
GEO; GSM1672058
Other Wikidata; Q54831215
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number13