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Cellosaurus HLaC-79 (CVCL_6648)

[Text version]

Cell line name HLaC-79
Synonyms HLaC 79; HLac 79; HLAC79; HLaC'79; HlaC79
Accession CVCL_6648
Resource Identification Initiative To cite this cell line use: HLaC-79 (RRID:CVCL_6648)
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=15495191).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Derived from metastatic site: Cervical lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_7000 (8029 NA )
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line

PubMed=6837290; DOI=10.3109/00016488309130956
Zenner H.P., Herrmann I.F., Bremer W., Stahl-Mauge C.
Head and neck carcinoma models. In vivo reproduction in athymic mice and in vitro culture.
Acta Oto-Laryngol. 95:371-381(1983)

PubMed=3138611; DOI=10.1177/019459988809800603
Wustrow T.P., Raffael A., Valet G.K.
Multiparametric flow cytometry of human squamous cell carcinoma lines from the head and neck.
Otolaryngol. Head Neck Surg. 98:552-557(1988)

Carey T.E.
Head and neck tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994)

PubMed=7543833; DOI=10.1007/BF00121908
Tomson A.M., Scholma J., Dijkhuizen T., Wijnakker A.P.M., van der Werf M., de Jong K.M.D., van Leeuwen M.B.M., Koning J.G.J.
Characterization of human larynx carcinoma cell lines HLaC'79 and HLaC'82: a common origin but diverged malignancies.
Clin. Exp. Metastasis 13:319-327(1995)

PubMed=8679156; DOI=10.1007/BF00178278
Koldovsky P., Haas I., Bier H., Ganzer U.
Immunohistochemical examination of 11 cell lines derived from human head and neck squamous cell carcinomas, their recurrences or metastases.
Eur. Arch. Otorhinolaryngol. 252:359-365(1995)

PubMed=15495191; DOI=10.1002/gcc.20119
Raschke S., Balz V., Efferth T., Schulz W.A., Florl A.R.
Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines.
Genes Chromosomes Cancer 42:58-67(2005)

PubMed=20947470; DOI=10.1186/2047-783X-15-8-337
Schuler P.J., Trellakis S., Greve J., Bas M., Bergmann C., Bolke E., Lehnerdt G., Mattheis S., Albers A.E., Brandau S., Lang S., Whiteside T.L., Bier H., Hoffmann T.K.
In vitro chemosensitivity of head and neck cancer cell lines.
Eur. J. Med. Res. 15:337-344(2010)

Anatomy/cell type resources BTO; BTO:0004021
Encyclopedic resources Wikidata; Q54889837
Polymorphism and mutation databases Cosmic; 932294
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number17