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Cellosaurus LS174T-HM7 (CVCL_6670)

[Text version]

Cell line name LS174T-HM7
Synonyms HM7; HM-7
Accession CVCL_6670
Resource Identification Initiative To cite this cell line use: LS174T-HM7 (RRID:CVCL_6670)
Comments Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Derived from sampling site: Colon.
Sequence variations Mutation; HGNC; 2514; CTNNB1; Simple; p.Ser45Phe (c.134C>T); ClinVar=VCV000017588; Zygosity=Unspecified (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1384 (LS174T)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,13
D3S135816,17
D5S81811,16
D7S82010.3,11
D8S117912,16
D13S31710,11
D16S53911,13
D18S5111,12
D21S1129,31
FGA21,22
Penta D10
Penta E15,16
TH016,7
TPOX8,9
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line databases/resources ColonAtlas; HM7
Ontologies BTO; BTO:0002921
EFO; EFO_0006787
Biological sample resources BioSample; SAMN03472364
Chemistry resources PharmacoDB; HM7_551_2019
Gene expression databases ArrayExpress; E-MTAB-2706
Other Wikidata; Q54903055
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number17