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Cellosaurus MCF-7M (CVCL_6672)

[Text version]

Cell line name MCF-7M
Synonyms MCF-7 M
Accession CVCL_6672
Resource Identification Initiative To cite this cell line use: MCF-7M (RRID:CVCL_6672)
Comments Doubling time: 1.4 days (PubMed=9671407).
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

PubMed=9671407; DOI=10.1038/sj.onc.1201814
Sweeney K.J., Swarbrick A., Sutherland R.L., Musgrove E.A.
Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells.
Oncogene 16:2865-2878(1998)

PubMed=10811993; DOI=10.3892/ijo.16.6.1179
Burow M.E., Weldon C.B., Chiang T.-C., Tang Y., Collins-Burow B.M., Rolfe K., Li S., McLachlan J.A., Beckman B.S.
Differences in protein kinase C and estrogen receptor alpha, beta expression and signaling correlate with apoptotic sensitivity of MCF-7 breast cancer cell variants.
Int. J. Oncol. 16:1179-1187(2000)

Other Wikidata; Q54904407
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number14