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Cellosaurus MCF-7N (CVCL_6673)

[Text version]

Cell line name MCF-7N
Synonyms MCF-7 N; MCF-7n
Accession CVCL_6673
Resource Identification Initiative To cite this cell line use: MCF-7N (RRID:CVCL_6673)
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Children:
CVCL_6674 (MCF-7TN-R)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=10811993; DOI=10.3892/ijo.16.6.1179
Burow M.E., Weldon C.B., Chiang T.-C., Tang Y., Collins-Burow B.M., Rolfe K., Li S., McLachlan J.A., Beckman B.S.
Differences in protein kinase C and estrogen receptor alpha, beta expression and signaling correlate with apoptotic sensitivity of MCF-7 breast cancer cell variants.
Int. J. Oncol. 16:1179-1187(2000)

PubMed=15138590; DOI=10.3892/ijo.24.6.1473
Weldon C.B., Parker A.P., Patten D., Elliott S., Tang Y., Frigo D.E., Dugan C.M., Coakley E.L., Butler N.N., Clayton J.L., Alam J., Curiel T.J., Beckman B.S., Jaffe B.M., Burow M.E.
Sensitization of apoptotically-resistant breast carcinoma cells to TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase signaling.
Int. J. Oncol. 24:1473-1480(2004)

Cross-references
Other Wikidata; Q54904408
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number14