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Cellosaurus MCF-7TN-R (CVCL_6674)

[Text version]
Cell line name MCF-7TN-R
Accession CVCL_6674
Resource Identification Initiative To cite this cell line use: MCF-7TN-R (RRID:CVCL_6674)
Comments Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6673 (MCF-7N)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=15138590; DOI=10.3892/ijo.24.6.1473
Weldon C.B., Parker A.P., Patten D., Elliott S., Tang Y., Frigo D.E., Dugan C.M., Coakley E.L., Butler N.N., Clayton J.L., Alam J., Curiel T.J., Beckman B.S., Jaffe B.M., Burow M.E.
Sensitization of apoptotically-resistant breast carcinoma cells to TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase signaling.
Int. J. Oncol. 24:1473-1480(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6674
Encyclopedic resources Wikidata; Q54904410
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19