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Cellosaurus TM-31 (CVCL_6735)

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Cell line name TM-31
Synonyms TM31
Accession CVCL_6735
Resource Identification Initiative To cite this cell line use: TM-31 (RRID:CVCL_6735)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 65 hours (at 50th passage), 62 hours (at 220th passage) (PubMed=11213969).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations TP53 p.Cys238Gly (c.712T>G) (PubMed=11213969).
Disease Astrocytoma (NCIt: C60781)
Neurofibromatosis type 1 (NCIt: C3273)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): RCB


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PubMed=11213969; DOI=10.3171/jns.2001.94.2.0301
Kurimoto M., Hirashima Y., Ogiichi T., Hamada H., Kamiyama H., Endo S.
Establishment and characterization of a novel malignant astrocytoma cell line derived from a tumor removed in a patient with neurofibromatosis type 1.
J. Neurosurg. 94:301-308(2001)

Couldwell W.T.
Astrocytoma cell line.
J. Neurosurg. 94:348-349(2001)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cell line collections BCRJ; 0379
RCB; RCB1731
Cell line databases/resources CCLE; TM31_CENTRAL_NERVOUS_SYSTEM
Ontologies CLO; CLO_0050635
Biological sample resources BioSample; SAMN03472072
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887707
GEO; GSM888800
Other Wikidata; Q54972649
Polymorphism and mutation databases IARC_TP53; 14834