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Cellosaurus C8161 (CVCL_6813)

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Cell line name C8161
Synonyms C81-61; C-8161
Accession CVCL_6813
Resource Identification Initiative To cite this cell line use: C8161 (RRID:CVCL_6813)
Comments Doubling time: 5.8 +- 1.9 days (PubMed=1671030).
Disease Cutaneous melanoma (NCIt: C3510)
Derived from metastatic site: Abdominal wall.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WS19 (C8161-GFP)CVCL_WS20 (C8161-PEDF)CVCL_0196 (C8161.9)
CVCL_6815 (neo6/C8161.1)CVCL_6816 (neo6/C8161.2)CVCL_6817 (neo6/C8161.3)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line

Sipes N.J., Bregman M.D., Meyskens F.L. Jr.
Stimulation of human metastatic melanoma colony-forming cells by an acid-sensitive factor in human platelet sonicate.
Cancer Res. 45:6268-6272(1985)

PubMed=3079741; DOI=10.1002/ijc.2910370117
Bregman M.D., Meyskens F.L. Jr.
Difluoromethylornithine enhances inhibition of melanoma cell growth in soft agar by dexamethasone, clone A interferon and retinoic acid.
Int. J. Cancer 37:101-107(1986)

Bregman M.D., Funk C., Fukushima M.
Inhibition of human melanoma growth by prostaglandin A, D, and J analogues.
Cancer Res. 46:2740-2744(1986)

PubMed=3667379; DOI=10.1016/0360-3016(87)90170-2
Yohem K.H., Bregman M.D., Meyskens F.L. Jr.
Effect of tumor colony definition on ionizing radiation survival curves of melanoma-colony forming cells.
Int. J. Radiat. Oncol. Biol. Phys. 13:1725-1733(1987)

PubMed=3348949; DOI=10.1038/bjc.1988.10
Yohem K.H., Slymen D.J., Bregman M.D., Meyskens F.L. Jr.
Radiation survival of murine and human melanoma cells utilizing two assay systems: monolayer and soft agar.
Br. J. Cancer 57:64-69(1988)

PubMed=1671030; DOI=10.1002/ijc.2910470211
Welch D.R., Bisi J.E., Miller B.E., Conaway D.H., Seftor E.A., Yohem K.H., Gilmore L.B., Seftor R.E.B., Nakajima M., Hendrix M.J.C.
Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell line.
Int. J. Cancer 47:227-237(1991)

Qin J.-Z., Stennett L., Bacon P., Bodner B., Hendrix M.J.C., Seftor R.E.B., Seftor E.A., Margaryan N.V., Pollock P.M., Curtis A., Trent J.M., Bennett F., Miele L., Nickoloff B.J.
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas.
Mol. Cancer Ther. 3:895-902(2004)

PubMed=19767774; DOI=10.1038/onc.2009.284
Orgaz J.L., Ladhani O., Hoek K.S., Fernandez-Barral A., Mihic D., Aguilera O., Seftor E.A., Bernad A., Rodriguez-Peralto J.L., Hendrix M.J.C., Volpert O.V., Jimenez B.
Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma.
Oncogene 28:4147-4161(2009)

Cell line databases/resources Lonza; 899
Ontologies BTO; BTO:0002016
Gene expression databases GEO; GSM952602
Other Wikidata; Q54808254
Polymorphism and mutation databases Cosmic; 905862
Cosmic; 1238116
Cosmic; 1247859
Cosmic; 1247864
Cosmic; 1247865
Cosmic; 1303034
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number14