ID   C8161
AC   CVCL_6813
SY   C81-61; C-8161
DR   BTO; BTO:0002016
DR   cancercelllines; CVCL_6813
DR   Cosmic; 905862
DR   Cosmic; 1238116
DR   Cosmic; 1247859
DR   Cosmic; 1247864
DR   Cosmic; 1247865
DR   Cosmic; 1303034
DR   GEO; GSM952602
DR   Lonza; 899
DR   Progenetix; CVCL_6813
DR   Wikidata; Q54808254
RX   PubMed=1671030;
RX   PubMed=3079741;
RX   PubMed=3348949;
RX   PubMed=3667379;
RX   PubMed=3698005;
RX   PubMed=3864528;
RX   PubMed=15299072;
RX   PubMed=19767774;
CC   Doubling time: 5.8 +- 1.9 days (PubMed=1671030).
CC   Derived from site: Metastatic; Abdominal wall; UBERON=UBERON_0003697.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Adult
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 18
//
RX   PubMed=1671030; DOI=10.1002/ijc.2910470211;
RA   Welch D.R., Bisi J.E., Miller B.E., Conaway D.H., Seftor E.A.,
RA   Yohem K.H., Gilmore L.B., Seftor R.E.B., Nakajima M., Hendrix M.J.C.;
RT   "Characterization of a highly invasive and spontaneously metastatic
RT   human malignant melanoma cell line.";
RL   Int. J. Cancer 47:227-237(1991).
//
RX   PubMed=3079741; DOI=10.1002/ijc.2910370117;
RA   Bregman M.D., Meyskens F.L. Jr.;
RT   "Difluoromethylornithine enhances inhibition of melanoma cell growth
RT   in soft agar by dexamethasone, clone A interferon and retinoic
RT   acid.";
RL   Int. J. Cancer 37:101-107(1986).
//
RX   PubMed=3348949; DOI=10.1038/bjc.1988.10;
RA   Yohem K.H., Slymen D.J., Bregman M.D., Meyskens F.L. Jr.;
RT   "Radiation survival of murine and human melanoma cells utilizing two
RT   assay systems: monolayer and soft agar.";
RL   Br. J. Cancer 57:64-69(1988).
//
RX   PubMed=3667379; DOI=10.1016/0360-3016(87)90170-2;
RA   Yohem K.H., Bregman M.D., Meyskens F.L. Jr.;
RT   "Effect of tumor colony definition on ionizing radiation survival
RT   curves of melanoma-colony forming cells.";
RL   Int. J. Radiat. Oncol. Biol. Phys. 13:1725-1733(1987).
//
RX   PubMed=3698005;
RA   Bregman M.D., Funk C., Fukushima M.;
RT   "Inhibition of human melanoma growth by prostaglandin A, D, and J
RT   analogues.";
RL   Cancer Res. 46:2740-2744(1986).
//
RX   PubMed=3864528;
RA   Sipes N.J., Bregman M.D., Meyskens F.L. Jr.;
RT   "Stimulation of human metastatic melanoma colony-forming cells by an
RT   acid-sensitive factor in human platelet sonicate.";
RL   Cancer Res. 45:6268-6272(1985).
//
RX   PubMed=15299072; DOI=10.1158/1535-7163.895.3.8;
RA   Qin J.-Z., Stennett L., Bacon P., Bodner B., Hendrix M.J.C.,
RA   Seftor R.E.B., Seftor E.A., Margaryan N.V., Pollock P.M., Curtis A.,
RA   Trent J.M., Bennett F., Miele L., Nickoloff B.J.;
RT   "p53-independent NOXA induction overcomes apoptotic resistance of
RT   malignant melanomas.";
RL   Mol. Cancer Ther. 3:895-902(2004).
//
RX   PubMed=19767774; DOI=10.1038/onc.2009.284;
RA   Orgaz J.L., Ladhani O., Hoek K.S., Fernandez-Barral A., Mihic D.,
RA   Aguilera O., Seftor E.A., Bernad A., Rodriguez-Peralto J.L.,
RA   Hendrix M.J.C., Volpert O.V., Jimenez B.;
RT   "Loss of pigment epithelium-derived factor enables migration,
RT   invasion and metastatic spread of human melanoma.";
RL   Oncogene 28:4147-4161(2009).
//