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Cellosaurus 10B10 (CVCL_6819)

[Text version]

Cell line name 10B10
Accession CVCL_6819
Resource Identification Initiative To cite this cell line use: 10B10 (RRID:CVCL_6819)
Comments Transfected with: VGNC; 98476; Pig IL12RB2.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for BAX p.Glu41Argfs*19 (c.121delG) (ClinVar=VCV000009512) (from parent cell line).
Heterozygous for BAX p.Glu41Glyfs*33 (c.121dupG) (ClinVar=VCV000009511) (from parent cell line).
Heterozygous for FBXW7 p.Arg505Cys (c.1513C>T) (ClinVar=VCV000069961) (from parent cell line).
Heterozygous for INPP5D p.Gln345Ter (c.1033C>T) (from parent cell line).
Heterozygous for INPP5D c.1097+1065_1097+1112del47 (from parent cell line).
Homozygous for MSH2 p.Arg711Ter (c.2131C>T) (ClinVar=VCV000090903) (from parent cell line).
Homozygous for MSH6 p.Phe1088Serfs*2 (c.3261delC) (ClinVar=VCV000089363) (from parent cell line).
Heterozygous for SYK p.Met34Hisfs*3 (c.98_99insG) (from parent cell line).
Heterozygous for TP53 p.Arg196Ter (c.586C>T) (ClinVar=VCV000043589) (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0367 (Jurkat E6.1)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=10B10
Publications

PubMed=12543551; DOI=10.1016/S0165-2427(02)00288-X
Kokuho T., Inumaru S., Watanabe S., Kubota T.
Cloning of porcine interleukin (IL)-12 receptor beta2 (IL-12Rbeta2) gene and its application to a rapid biological assay for human/porcine IL-12.
Vet. Immunol. Immunopathol. 91:155-160(2003)

Cross-references
Other Wikidata; Q54399879
Entry history
Entry creation04-Apr-2012
Last entry update12-Jan-2021
Version number17