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Cellosaurus C57MG (CVCL_6824)

[Text version]

Cell line name C57MG
Synonyms C57mg
Accession CVCL_6824
Resource Identification Initiative To cite this cell line use: C57MG (RRID:CVCL_6824)
Comments Characteristics: Used to study Wnt signalling.
Omics: Transcriptome analysis.
Derived from sampling site: Mammary gland; epithelial cells.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_G295 (C57MG-A5)CVCL_LF86 (C57MG/2-69-23)CVCL_LF85 (C57MG/Wnt-1)
Sex of cell Female
Age at sampling 23W
Category Spontaneously immortalized cell line
STR profile Source(s): Millipore

Markers:
Mouse STR 1-116
Mouse STR 1-217
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-221.3
Mouse STR 5-517
Mouse STR 6-418
Mouse STR 6-715
Mouse STR 7-126.2
Mouse STR 8-116
Mouse STR 11-215.3
Mouse STR 12-117
Mouse STR 13-118
Mouse STR 15-322.3
Mouse STR 17-215
Mouse STR 18-316
Mouse STR 19-213
Mouse STR X-128

Run an STR similarity search on this cell line
Publications

PubMed=213889; DOI=10.1016/0042-6822(78)90328-8
Vaidya A.B., Lasfargues E.Y., Sheffield J.B., Coutinho W.G.
Murine mammary tumor virus (MuMTV) infection of an epithelial cell line established from C57BL/6 mouse mammary glands.
Virology 90:12-22(1978)

PubMed=8065359; DOI=10.1128/MCB.14.9.6278
Wong G.T., Gavin B.J., McMahon A.P.
Differential transformation of mammary epithelial cells by Wnt genes.
Mol. Cell. Biol. 14:6278-6286(1994)

PubMed=8180133
Olson D.J., Papkoff J.
Regulated expression of Wnt family members during proliferation of C57mg mammary cells.
Cell Growth Differ. 5:197-206(1994)

PubMed=9488439; DOI=10.1128/MCB.18.3.1248
Korinek V., Barker N., Willert K., Molenaar M., Roose J., Wagenaar G., Markman M., Lamers W., Destree O., Clevers H.
Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.
Mol. Cell. Biol. 18:1248-1256(1998)

PubMed=11358845
Szeto W., Jiang W., Tice D.A., Rubinfeld B., Hollingshead P.G., Fong S.E., Dugger D.L., Pham T., Yansura D.G., Wong T.A., Grimaldi J.C., Corpuz R.T., Singh J.S., Frantz G.D., Devaux B., Crowley C.W., Schwall R.H., Eberhard D.A., Rastelli L., Polakis P., Pennica D.
Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid.
Cancer Res. 61:4197-4205(2001)

PubMed=11832495; DOI=10.1074/jbc.M200334200
Tice D.A., Szeto W., Soloviev I., Rubinfeld B., Fong S.E., Dugger D.L., Winer J., Williams P.M., Wieand D., Smith V., Schwall R.H., Pennica D., Polakis P.
Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling.
J. Biol. Chem. 277:14329-14335(2002)

PubMed=22238613; DOI=10.1371/journal.pone.0029455
Baljinnyam B., Klauzinska M., Saffo S., Callahan R., Rubin J.S.
Recombinant R-spondin2 and Wnt3a up- and down-regulate novel target genes in C57MG mouse mammary epithelial cells.
PLoS ONE 7:E29455-E29455(2012)

Cross-references
Cell line collections Millipore; SCC273
Cell line databases/resources Lonza; 122
Ontologies BTO; BTO:0003569
Gene expression databases GEO; GSE32096
Other Wikidata; Q54808202
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number10