ID   C57MG
AC   CVCL_6824
SY   C57mg
DR   BTO; BTO:0003569
DR   GEO; GSE32096
DR   Lonza; 122
DR   Millipore; SCC273
DR   Wikidata; Q54808202
RX   PubMed=213889;
RX   PubMed=8065359;
RX   PubMed=8180133;
RX   PubMed=9488439;
RX   PubMed=11358845;
RX   PubMed=11832495;
RX   PubMed=22238613;
CC   Characteristics: Used to study Wnt signalling.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
CC   Breed/subspecies: C57BL/6.
ST   Source(s): Millipore
ST   Mouse STR 1-1: 16
ST   Mouse STR 1-2: 17
ST   Mouse STR 11-2: 15.3
ST   Mouse STR 12-1: 17
ST   Mouse STR 13-1: 18
ST   Mouse STR 15-3: 22.3
ST   Mouse STR 17-2: 15
ST   Mouse STR 18-3: 16
ST   Mouse STR 19-2: 13
ST   Mouse STR 2-1: 16
ST   Mouse STR 3-2: 14
ST   Mouse STR 4-2: 21.3
ST   Mouse STR 5-5: 17
ST   Mouse STR 6-4: 18
ST   Mouse STR 6-7: 15
ST   Mouse STR 7-1: 26.2
ST   Mouse STR 8-1: 16
ST   Mouse STR X-1: 28
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   23W
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 13
//
RX   PubMed=213889; DOI=10.1016/0042-6822(78)90328-8;
RA   Vaidya A.B., Lasfargues E.Y., Sheffield J.B., Coutinho W.G.;
RT   "Murine mammary tumor virus (MuMTV) infection of an epithelial cell
RT   line established from C57BL/6 mouse mammary glands.";
RL   Virology 90:12-22(1978).
//
RX   PubMed=8065359; DOI=10.1128/mcb.14.9.6278-6286.1994;
RA   Wong G.T., Gavin B.J., McMahon A.P.;
RT   "Differential transformation of mammary epithelial cells by Wnt
RT   genes.";
RL   Mol. Cell. Biol. 14:6278-6286(1994).
//
RX   PubMed=8180133;
RA   Olson D.J., Papkoff J.;
RT   "Regulated expression of Wnt family members during proliferation of
RT   C57mg mammary cells.";
RL   Cell Growth Differ. 5:197-206(1994).
//
RX   PubMed=9488439; DOI=10.1128/mcb.18.3.1248;
RA   Korinek V., Barker N., Willert K., Molenaar M., Roose J.P., Wagenaar G.,
RA   Markman M., Lamers W., Destree O., Clevers H.C.;
RT   "Two members of the Tcf family implicated in Wnt/beta-catenin
RT   signaling during embryogenesis in the mouse.";
RL   Mol. Cell. Biol. 18:1248-1256(1998).
//
RX   PubMed=11358845;
RA   Szeto W., Jiang W., Tice D.A., Rubinfeld B., Hollingshead P.G.,
RA   Fong S.E., Dugger D.L., Pham T., Yansura D.G., Wong T.A.,
RA   Grimaldi J.C., Corpuz R.T., Singh J.S., Frantz G.D., Devaux B.,
RA   Crowley C.W., Schwall R.H., Eberhard D.A., Rastelli L., Polakis P.,
RA   Pennica D.;
RT   "Overexpression of the retinoic acid-responsive gene Stra6 in human
RT   cancers and its synergistic induction by Wnt-1 and retinoic acid.";
RL   Cancer Res. 61:4197-4205(2001).
//
RX   PubMed=11832495; DOI=10.1074/jbc.M200334200;
RA   Tice D.A., Szeto W., Soloviev I., Rubinfeld B., Fong S.E.,
RA   Dugger D.L., Winer J., Williams P.M., Wieand D., Smith V.,
RA   Schwall R.H., Pennica D., Polakis P.;
RT   "Synergistic induction of tumor antigens by Wnt-1 signaling and
RT   retinoic acid revealed by gene expression profiling.";
RL   J. Biol. Chem. 277:14329-14335(2002).
//
RX   PubMed=22238613; DOI=10.1371/journal.pone.0029455;
RA   Baljinnyam B., Klauzinska M., Saffo S., Callahan R., Rubin J.S.;
RT   "Recombinant R-spondin2 and Wnt3a up- and down-regulate novel target
RT   genes in C57MG mouse mammary epithelial cells.";
RL   PLoS ONE 7:E29455-E29455(2012).
//