Cellosaurus logo
expasy logo

Cellosaurus REF52 (CVCL_6848)

[Text version]
Cell line name REF52
Synonyms REF-52; REF 52; Rat Embryo Fibroblast 52
Accession CVCL_6848
Resource Identification Initiative To cite this cell line use: REF52 (RRID:CVCL_6848)
Comments Omics: Proteome analysis by 2D-DE.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344.
Hierarchy Children:
CVCL_GR59 (REF-4A)CVCL_B5G1 (REF-WT10A)CVCL_B5G2 (REF-WT1A)
CVCL_B5G3 (REF-WT2A)CVCL_B5G4 (REF-WT6A)
Sex of cell Sex unspecified
Age at sampling 14FD
Category Spontaneously immortalized cell line
Publications

PubMed=7314451; DOI=10.1016/0042-6822(81)90126-4
Logan J., Nicolas J.-C., Topp W.C., Girard M.P., Shenk T.E., Levine A.J.
Transformation by adenovirus early region 2A temperature-sensitive mutants and their revertants.
Virology 115:419-422(1981)

PubMed=6133866; DOI=10.1016/S0021-9258(18)32460-8
Matsumura F., Yamashiro-Matsumura S., Lin J.J.-C.
Isolation and characterization of tropomyosin-containing microfilaments from cultured cells.
J. Biol. Chem. 258:6636-6644(1983)

PubMed=6315714; DOI=10.1016/S0021-9258(17)44009-9
Matsumura F., Lin J.J.-C., Yamashiro-Matsumura S., Thomas G.P., Topp W.C.
Differential expression of tropomyosin forms in the microfilaments isolated from normal and transformed rat cultured cells.
J. Biol. Chem. 258:13954-13964(1983)

PubMed=3510745; DOI=10.1016/0092-8674(86)90462-9
Franza B.R. Jr., Maruyama K., Garrels J.I., Ruley H.E.
In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.
Cell 44:409-418(1986)

PubMed=2830582
Kohl N.E., Ruley H.E.
Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes.
Oncogene 2:41-48(1987)

PubMed=2564397; DOI=10.1016/S0021-9258(18)83730-9
Garrels J.I., Franza B.R. Jr.
Transformation-sensitive and growth-related changes of protein synthesis in REF52 cells. A two-dimensional gel analysis of SV40-, adenovirus-, and Kirsten murine sarcoma virus-transformed rat cells using the REF52 protein database.
J. Biol. Chem. 264:5299-5312(1989)

Cross-references
Cell line databases/resources TOKU-E; 3889
Anatomy/cell type resources BTO; BTO:0001955
Encyclopedic resources Wikidata; Q54949702
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number12