ID   REF52
AC   CVCL_6848
SY   REF-52; REF 52; Rat Embryo Fibroblast 52
DR   BTO; BTO:0001955
DR   TOKU-E; 3889
DR   Wikidata; Q54949702
RX   PubMed=2564397;
RX   PubMed=2830582;
RX   PubMed=3510745;
RX   PubMed=6133866;
RX   PubMed=6315714;
RX   PubMed=7314451;
CC   Omics: Proteome analysis by 2D-DE.
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: Fischer 344.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Sex unspecified
AG   14FD
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 12
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RX   PubMed=2564397; DOI=10.1016/S0021-9258(18)83730-9;
RA   Garrels J.I., Franza B.R. Jr.;
RT   "Transformation-sensitive and growth-related changes of protein
RT   synthesis in REF52 cells. A two-dimensional gel analysis of SV40-,
RT   adenovirus-, and Kirsten murine sarcoma virus-transformed rat cells
RT   using the REF52 protein database.";
RL   J. Biol. Chem. 264:5299-5312(1989).
//
RX   PubMed=2830582;
RA   Kohl N.E., Ruley H.E.;
RT   "Role of c-myc in the transformation of REF52 cells by viral and
RT   cellular oncogenes.";
RL   Oncogene 2:41-48(1987).
//
RX   PubMed=3510745; DOI=10.1016/0092-8674(86)90462-9;
RA   Franza B.R. Jr., Maruyama K., Garrels J.I., Ruley H.E.;
RT   "In vitro establishment is not a sufficient prerequisite for
RT   transformation by activated ras oncogenes.";
RL   Cell 44:409-418(1986).
//
RX   PubMed=6133866; DOI=10.1016/S0021-9258(18)32460-8;
RA   Matsumura F., Yamashiro-Matsumura S., Lin J.J.-C.;
RT   "Isolation and characterization of tropomyosin-containing
RT   microfilaments from cultured cells.";
RL   J. Biol. Chem. 258:6636-6644(1983).
//
RX   PubMed=6315714; DOI=10.1016/S0021-9258(17)44009-9;
RA   Matsumura F., Lin J.J.-C., Yamashiro-Matsumura S., Thomas G.P.,
RA   Topp W.C.;
RT   "Differential expression of tropomyosin forms in the microfilaments
RT   isolated from normal and transformed rat cultured cells.";
RL   J. Biol. Chem. 258:13954-13964(1983).
//
RX   PubMed=7314451; DOI=10.1016/0042-6822(81)90126-4;
RA   Logan J., Nicolas J.-C., Topp W.C., Girard M.P., Shenk T.E., Levine A.J.;
RT   "Transformation by adenovirus early region 2A temperature-sensitive
RT   mutants and their revertants.";
RL   Virology 115:419-422(1981).
//