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Cellosaurus Tca8113 (CVCL_6851)

[Text version]
Cell line name Tca8113
Synonyms TCA8113; Tca-8113
Accession CVCL_6851
Resource Identification Initiative To cite this cell line use: Tca8113 (RRID:CVCL_6851)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28851942). Originally thought to originate from a female patient with a tongue squamous cell carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00578.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Miscellaneous: Formerly the CCRID database had 3 entries describing this cell line (3111C0001CCC000296, 3131C0001000700077, 3142C0001000000067). They were one of the sources for the STR profile of this entry.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_7906 (Tca8113-P160)CVCL_7907 (Tca8113-P60)CVCL_9U53 (Tca8113/CBP [Chengdu])
CVCL_T058 (Tca8113/CBP [Chongqing])CVCL_9U54 (Tca8113/PYM [Changsha])CVCL_9U55 (Tca8113/PYM [Chengdu])
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): CCRID; PubMed=26116706; PubMed=28851942

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D6S104318,19
D7S8208,12
D8S117912,13
D12S39120,25
D13S31712,13.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=3464389
Xu X.-Q., He R.-G., Zhou X.-J., Zhang X.-L., Yu W.-L., Xu L.-Z., Liu Y.-F.
Chromosome study on the Tca8113 cell line derived from squamous cell carcinoma of the human tongue.
Zhonghua Zhong Liu Za Zhi 8:112-114(1986)

PubMed=26116706; DOI=10.1096/fj.14-266718
Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)

PubMed=28851942; DOI=10.1038/s41598-017-09660-w
Bian X.-C., Yang Z.-L., Feng H.-L., Sun H., Liu Y.-Q.
A combination of species identification and STR profiling identifies cross-contaminated cells from 482 human tumor cell lines.
Sci. Rep. 7:9774-9774(2017)

Cross-references
Cell line collections (Providers) KCB; KCB 93034YJ
Anatomy/cell type resources BTO; BTO:0006058
Encyclopedic resources Wikidata; Q54971846
Polymorphism and mutation databases Cosmic; 851222
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number17