ID   ACCS
AC   CVCL_6876
SY   ACC-S
DR   BioSample; SAMN03151936
DR   BioSample; SAMN10989595
DR   CCLE; ACCS_URINARY_TRACT
DR   Cell_Model_Passport; SIDM01166
DR   DepMap; ACH-001011
DR   IARC_TP53; 28390
DR   PharmacoDB; ACCS_53_2019
DR   Wikidata; Q54608335
RX   DOI=10.1007/0-306-46872-7_9;
RX   DOI=10.4103/2468-5585.200513;
RX   PubMed=2162254;
RX   PubMed=19557180;
RX   PubMed=20143388;
RX   PubMed=31068700;
WW   http://iclac.org/wp-content/uploads/Cross-Contaminations_v11_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a T24 derivative (PubMed=19557180; PubMed=20143388). Originally thought to originate from a 56 year old female patient with a salivary gland adenoid cystic carcinoma.
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00361.
CC   Population: Caucasian; Swedish.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (CCLE).
CC   Omics: Deep exome analysis.
CC   Derived from sampling site: Urinary bladder.
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0554 ! T24
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 23-09-21; Version: 24
//
RX   DOI=10.1007/0-306-46872-7_9;
RA   Sato M.;
RT   "Salivary gland tumors.";
RL   (In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.161-178; Kluwer Academic Publishers; New York (1999).
//
RX   DOI=10.4103/2468-5585.200513;
RA   Liu N.-N., Zhang S.-L., Chen W.;
RT   "The cross-contaminated cell lines of adenoid cystic carcinoma:
RT   a crucial concern.";
RL   Transl. Surg. 2:10-13(2017).
//
RX   PubMed=2162254;
RA   Shirasuna K., Watatani K., Furusawa H., Saka M., Morioka S.,
RA   Yoshioka H., Matsuya T.;
RT   "Biological characterization of pseudocyst-forming cell lines from
RT   human adenoid cystic carcinomas of minor salivary gland origin.";
RL   Cancer Res. 50:4139-4145(1990).
//
RX   PubMed=19557180; DOI=10.1371/journal.pone.0006040;
RA   Phuchareon J., Ohta Y., Woo J.M., Eisele D.W., Tetsu O.;
RT   "Genetic profiling reveals cross-contamination and misidentification
RT   of 6 adenoid cystic carcinoma cell lines: ACC2, ACC3, ACCM, ACCNS,
RT   ACCS and CAC2.";
RL   PLoS ONE 4:E6040-E6040(2009).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//