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Cellosaurus QSG-7701 (CVCL_6944)

[Text version]

Cell line name QSG-7701
Synonyms QSG7701
Accession CVCL_6944
Resource Identification Initiative To cite this cell line use: QSG-7701 (RRID:CVCL_6944)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28807831). Originally thought to originate from an immortalized but non-transformed hepatocytes from a 35 year old female.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00553.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from sampling site: Uterus; cervix.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): CCRID; PubMed=26116706

Markers:
AmelogeninX
CSF1PO10
D2S133817
D3S135815,18
D5S81811,12
D7S82012
D8S117912
D13S31713.3
D16S5399,10
D18S5116
D19S43313
D21S1127,28
FGA18,21
Penta D8,15
Penta E7,8,17
TH017
TPOX12
vWA16,18

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
Publications

CLPUB00100
Zhu D.-H., Wang J.-B.
Establishment and comparison of non-malignant liver cell QSG-7701 and liver cancer cells.
Zhong Liu Fang Zhi Yan Jiu 5:7-9(1979)

PubMed=20564214; DOI=10.1002/jcb.22632
Zhang F., Xu R., Zhao M.J.
QSG-7701 human hepatocytes form polarized acini in three-dimensional culture.
J. Cell. Biochem. 110:1175-1186(2010)

PubMed=26116706; DOI=10.1096/fj.14-266718
Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)

PubMed=28807831; DOI=10.1016/j.jhep.2017.08.002
Rebouissou S., Zucman-Rossi J., Moreau R., Qiu Z.-X., Hui L.-J.
Note of caution: contaminations of hepatocellular cell lines.
J. Hepatol. 67:896-897(2017)

Cross-references
Cell line databases/resources CCRID; 3131C0001000200007
TOKU-E; 4021
Other Wikidata; Q54948938
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number17