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Cellosaurus SF188 (CVCL_6948)

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Cell line name SF188
Synonyms SF-188; SF 188
Accession CVCL_6948
Resource Identification Initiative To cite this cell line use: SF188 (RRID:CVCL_6948)
Comments Doubling time: 26 hours (PubMed=19365568).
Omics: CNV analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Brain; right frontal lobe.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D590 (SF-xL )
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
STR profile Source(s): Genomics_Center_BCF_Technion; PubMed=22570425

Penta D14
Penta E10,13

Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20150905213317/btrctissuecore.ucsf.edu/tbank/Cell_Line%20Notice.html

PubMed=3708752; DOI=10.1093/carcin/7.6.879
Bodell W.J., Aida T., Berger M.S., Rosenblum M.L.
Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.
Carcinogenesis 7:879-883(1986)

PubMed=2829496; DOI=10.1007/BF00686798
Rutka J.T., Giblin J.R., Dougherty D.Y., Liu H.C., McCulloch J.R., Bell C.W., Stern R.S., Wilson C.B., Rosenblum M.L.
Establishment and characterization of five cell lines derived from human malignant gliomas.
Acta Neuropathol. 75:92-103(1987)

Nister M., Westermark B.
Human glioma cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.17-42; Academic Press; New York (1994)

PubMed=9614553; DOI=10.1038/sj.gt.3300605
Tada M., Sakuma S., Iggo R.D., Saya H., Sawamura Y., Fujiwara T., Roth J.A.
Monitoring adenoviral p53 transduction efficiency by yeast functional assay.
Gene Ther. 5:339-344(1998)

Ali-Osman F.
Brain tumors.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York (1999)

PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x
Ishii N., Maier D., Merlo A., Tada M., Sawamura Y., Diserens A.-C., Van Meir E.G.
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.
Brain Pathol. 9:469-479(1999)

PubMed=19033189; DOI=10.1073/pnas.0810199105
Wise D.R., DeBerardinis R.J., Mancuso A., Sayed N., Zhang X.-Y., Pfeiffer H.K., Nissim I., Daikhin E., Yudkoff M., McMahon S.B., Thompson C.B.
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
Proc. Natl. Acad. Sci. U.S.A. 105:18782-18787(2008)

PubMed=19365568; DOI=10.1371/journal.pone.0005209
Bax D.A., Little S.E., Gaspar N., Perryman L., Marshall L., Viana-Pereira M., Jones T.A., Williams R.D., Grigoriadis A., Vassal G., Workman P., Sheer D., Reis R.M., Pearson A.D.J., Hargrave D., Jones C.
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.
PLoS ONE 4:E5209-E5209(2009)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22570425; DOI=10.1093/neuonc/nos072
Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K., Hamou M.-F., Delorenzi M., Hegi M.E.
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=25628092; DOI=10.1038/bjc.2015.16
Cockle J.V., Picton S., Levesley J., Ilett E., Carcaboso A.M., Short S., Steel L.P., Melcher A., Lawler S.E., Bruning-Richardson A.
Cell migration in paediatric glioma; characterisation and potential therapeutic targeting.
Br. J. Cancer 112:693-703(2015)

Cell line collections Millipore; SCC282
Anatomy/cell type resources BTO; BTO:0002824
Chemistry resources ChEMBL-Cells; CHEMBL3307445
ChEMBL-Targets; CHEMBL614906
Encyclopedic resources Wikidata; Q54952896
Gene expression databases GEO; GSM2197886
GEO; GSM2197887
GEO; GSM2197888
GEO; GSM2197889
GEO; GSM2197890
GEO; GSM2197891
Polymorphism and mutation databases Cosmic; 849884
Cosmic; 1875113
IARC_TP53; 5708
Progenetix; CVCL_6948
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number20