Cellosaurus cell line SF188 (CVCL_6948)

• Mutation; HGNC; 11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Homozygous (PubMed=9614553; PubMed=10416987).
  

PubMed=3708752; DOI=10.1093/carcin/7.6.879
Bodell W.J., Aida T., Berger M.S., Rosenblum M.L.
Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.
Carcinogenesis 7:879-883(1986)

PubMed=2829496; DOI=10.1007/BF00686798
Rutka J.T., Giblin J.R., Dougherty D.Y., Liu H.C., McCulloch J.R., Bell C.W., Stern R.S., Wilson C.B., Rosenblum M.L.
Establishment and characterization of five cell lines derived from human malignant gliomas.
Acta Neuropathol. 75:92-103(1987)

DOI=10.1016/B978-0-12-333530-2.50005-8
Nister M., Westermark B.
Human glioma cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.17-42; Academic Press; New York (1994)

PubMed=9614553; DOI=10.1038/sj.gt.3300605
Tada M., Sakuma S., Iggo R.D., Saya H., Sawamura Y., Fujiwara T., Roth J.A.
Monitoring adenoviral p53 transduction efficiency by yeast functional assay.
Gene Ther. 5:339-344(1998)

DOI=10.1007/0-306-46861-1_11
Ali-Osman F.
Brain tumors.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York (1999)

PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x
Ishii N., Maier D., Merlo A., Tada M., Sawamura Y., Diserens A.-C., Van Meir E.G.
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.
Brain Pathol. 9:469-479(1999)

PubMed=19033189; DOI=10.1073/pnas.0810199105
Wise D.R., DeBerardinis R.J., Mancuso A., Sayed N., Zhang X.-Y., Pfeiffer H.K., Nissim I., Daikhin E., Yudkoff M., McMahon S.B., Thompson C.B.
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
Proc. Natl. Acad. Sci. U.S.A. 105:18782-18787(2008)

PubMed=19365568; DOI=10.1371/journal.pone.0005209
Bax D.A., Little S.E., Gaspar N., Perryman L., Marshall L., Viana-Pereira M., Jones T.A., Williams R.D., Grigoriadis A., Vassal G., Workman P., Sheer D., Reis R.M., Pearson A.D.J., Hargrave D., Jones C.
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.
PLoS ONE 4:E5209-E5209(2009)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22570425; DOI=10.1093/neuonc/nos072
Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K., Hamou M.-F., Delorenzi M., Hegi M.E.
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=25628092; DOI=10.1038/bjc.2015.16
Cockle J.V., Picton S., Levesley J., Ilett E., Carcaboso A.M., Short S., Steel L.P., Melcher A., Lawler S.E., Bruning-Richardson A.
Cell migration in paediatric glioma; characterisation and potential therapeutic targeting.
Br. J. Cancer 112:693-703(2015)

PubMed=29760046; DOI=10.1158/0008-5472.CAN-17-3691
Pal S., Kozono D., Yang X.-D., Fendler W., Fitts W., Ni J., Alberta J.A., Zhao J., Liu K.X., Bian J., Truffaux N., Weiss W.A., Resnick A.C., Bandopadhayay P., Ligon K.L., DuBois S.G., Mueller S., Chowdhury D., Haas-Kogan D.A.
Dual HDAC and PI3K inhibition abrogates NFkappaB- and FOXM1-mediated DNA damage response to radiosensitize pediatric high-grade gliomas.
Cancer Res. 78:4007-4021(2018)