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Cellosaurus HPLA-A3 (CVCL_6G77)

[Text version]

Cell line name HPLA-A3
Accession CVCL_6G77
Resource Identification Initiative To cite this cell line use: HPLA-A3 (RRID:CVCL_6G77)
Comments Transfected with: HGNC; 7968; NR1I2.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Sequence variations NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

PubMed=22687401; DOI=10.1248/bpb.35.677
Sekimoto M., Sano S., Hosaka T., Nemoto K., Degawa M.
Establishment of a stable human cell line, HPL-A3, for use in reporter gene assays of cytochrome P450 3A inducers.
Biol. Pharm. Bull. 35:677-685(2012)

Other Wikidata; Q54890298
Entry history
Entry creation23-Feb-2016
Last entry update02-Jul-2020
Version number8