Cellosaurus cell line Ma-2 (CVCL_7060)

• Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=10536175; PubMed=20557307).
  

PubMed=1650680; DOI=10.1378/chest.100.2.429
Masuda N., Fukuoka M., Takada M., Kudoh S., Kusunoki Y.
Establishment and characterization of 20 human non-small cell lung cancer cell lines in a serum-free defined medium (ACL-4).
Chest 100:429-438(1991)

PubMed=9393586; DOI=10.1007/s004320050101
Shimizu E., Zhao M.-R., Shinohara A., Namikawa O., Ogura T., Masuda N., Takada M., Fukuoka M., Sone S.
Differential expressions of cyclin A and the retinoblastoma gene product in histological subtypes of lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 123:533-538(1997)

PubMed=10536175; DOI=10.3892/ijo.15.5.927
Fujita T., Kiyama M., Tomizawa Y., Kohno T., Yokota J.
Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.
Int. J. Oncol. 15:927-934(1999)

PubMed=11005564; DOI=10.1038/sj.neo.7900094
Kohno T., Sato T., Takakura S., Takei K., Inoue K., Nishioka M., Yokota J.
Mutation and expression of the DCC gene in human lung cancer.
Neoplasia 2:300-305(2000)

PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x
Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.
Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
Cancer Sci. 101:1891-1896(2010)