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Cellosaurus NA (CVCL_7082)

Cell line name NA
Accession CVCL_7082
Resource Identification Initiative To cite this cell line use: NA (RRID:CVCL_7082)
Comments Population: Japanese.
Doubling time: ~21.6 hours (DOI=10.5794/jjoms.36.868).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220His (c.658T>C); ClinVar=VCV000376687; Zygosity=Unspecified (PubMed=1570156).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 86Y
Category Cancer cell line
Publications

DOI=10.5794/jjoms.36.868
Yoshiya M.
A fibronectin-producing cell line established from a human squamous cell carcinoma of the tongue and its characterization.
Nihon Koku Geka Gakkai Zasshi 36:868-880(1990)

PubMed=1570156
Sakai E., Tsuchida N.
Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
Oncogene 7:927-933(1992)

PubMed=10069537; DOI=10.1111/j.1600-0714.1999.tb02006.x
Hoteiya T., Hayashi E., Satomura K., Kamata N., Nagayama M.
Expression of E-cadherin in oral cancer cell lines and its relationship to invasiveness in SCID mice in vivo.
J. Oral Pathol. Med. 28:107-111(1999)

PubMed=17052259; DOI=10.1111/j.1349-7006.2006.00343.x
Kozaki K.-i., Imoto I., Pimkhaokham A., Hasegawa S., Tsuda H., Omura K., Inazawa J.
PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma.
Cancer Sci. 97:1351-1358(2006)

PubMed=17599052; DOI=10.1038/sj.onc.1210589
Suzuki E., Imoto I., Pimkhaokham A., Nakagawa T., Kamata N., Kozaki K.-i., Amagasa T., Inazawa J.
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Oncogene 26:7921-7932(2007)

PubMed=18097548; DOI=10.3892/ijo.32.1.101
Murugan A.K., Hong N.T., Fukui Y., Munirajan A.K., Tsuchida N.
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.
Int. J. Oncol. 32:101-111(2008)

Cross-references
Cell line databases/resources CGH-DB; 356-2
Anatomy/cell type resources BTO; BTO:0004003
Encyclopedic resources Wikidata; Q54907353
Polymorphism and mutation databases Cosmic; 930336
Cosmic; 974314
Cosmic; 1046035
Cosmic; 1123037
Cosmic; 1317412
IARC_TP53; 1104
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14