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Cellosaurus SCMC-ES2 (CVCL_7124)

[Text version]
Cell line name SCMC-ES2
Synonyms SCMC-ES-2; Saitama Children's Medical Center-Ewing Sarcoma 2
Accession CVCL_7124
Resource Identification Initiative To cite this cell line use: SCMC-ES2 (RRID:CVCL_7124)
Comments Population: Japanese.
Sequence variations
  • Gene fusion; HGNC; 3446; ERG + HGNC; 3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (PubMed=7591257).
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Unspecified (PubMed=8221663).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Publications

DOI=10.2198/sbk.34.289
Mizusawa H.
Operation of the JCRB cell bank and isoenzyme.
Seibutsu Butsuri Kagaku 34:289-292(1990)

CLPUB00110
Hayashi Y., Hanada R., Moriwaki K., Yamamoto K., Imaizumi S., Hirata A., Nishida T.
Establishment and characterization of cell lines derived from malignant tumors in children.
Saitama Shoni Iryo Senta Igaku-shi 8:16-23(1991)

PubMed=8221663
Komuro H., Hayashi Y., Kawamura M., Hayashi K., Kaneko Y., Kamoshita S., Hanada R., Yamamoto K., Hongo T., Yamada M., Tsuchida Y.
Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas.
Cancer Res. 53:5284-5288(1993)

PubMed=7591257; DOI=10.1002/ijc.2910630407
Ida K., Kobayashi S., Taki T., Hanada R., Bessho F., Yamamori S., Sugimoto T., Ohki M., Hayashi Y.
EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor.
Int. J. Cancer 63:500-504(1995)

Cross-references
Cell line collections (Providers) JCRB; NIHS0049 - Discontinued
Cell line databases/resources cancercelllines; CVCL_7124
Encyclopedic resources Wikidata; Q54952451
Polymorphism and mutation databases Cosmic; 1078361
Cosmic; 1381108
IARC_TP53; 1274
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19