ID   U-1285dox
AC   CVCL_7154
SY   U-1285dox(900)
DR   BTO; BTO:0002391
DR   cancercelllines; CVCL_7154
DR   Wikidata; Q54973512
RX   PubMed=12766562;
CC   Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Unspecified; Note=Splice acceptor mutation (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7153 ! U-1285
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 15
//
RX   PubMed=12766562;
RA   Jonsson-Videsater K., Andersson G., Bergh J., Paul C.;
RT   "Doxorubicin-resistant, MRP1-expressing U-1285 cells are sensitive to
RT   idarubicin.";
RL   Ther. Drug Monit. 25:331-339(2003).
//