ID   CHO-S
AC   CVCL_7183
SY   CHO-s; CHOS
DR   CLO; CLO_0037216
DR   GEO; GSM1968575
DR   GEO; GSM1968576
DR   Lonza; 842
DR   Wikidata; Q54813102
RX   DOI=10.3390/pr1030296;
RX   DOI=10.3390/pr5020020;
RX   PubMed=837451;
RX   PubMed=4585080;
RX   PubMed=23873082;
RX   PubMed=26993211;
RX   PubMed=28876938;
RX   PubMed=32985598;
RX   PubMed=34050613;
RX   PubMed=36610518;
WW   https://www.thermofisher.com/order/catalog/product/A1155701
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-207.html
CC   Omics: Deep proteome analysis.
CC   Omics: Genome sequenced.
CC   Omics: miRNA expression profiling.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0213 ! CHO
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 22
//
RX   DOI=10.3390/pr1030296;
RA   Wurm F.M.;
RT   "CHO quasispecies -- implications for manufacturing processes.";
RL   Processes 1:296-311(2013).
//
RX   DOI=10.3390/pr5020020;
RA   Wurm F.M., Wurm M.J.;
RT   "Cloning of CHO cells, productivity and genetic stability -- a
RT   discussion.";
RL   Processes 5:20.1-20.13(2017).
//
RX   PubMed=837451; DOI=10.1016/0092-8674(77)90224-0;
RA   Konrad M.W., Storrie B., Glaser D.A., Thompson L.H.;
RT   "Clonal variation in colony morphology and growth of CHO cells
RT   cultured on agar.";
RL   Cell 10:305-312(1977).
//
RX   PubMed=4585080; DOI=10.1016/S0091-679X(08)60052-7;
RA   Thompson L.H., Baker R.M.;
RT   "Isolation of mutants of cultured mammalian cells.";
RL   Methods Cell Biol. 6:209-281(1973).
//
RX   PubMed=23873082; DOI=10.1038/nbt.2624;
RA   Lewis N.E., Liu X., Li Y.-X., Nagarajan H., Yerganian G., O'Brien E.,
RA   Bordbar A., Roth A.M., Rosenbloom J., Bian C., Xie M., Chen W.-B.,
RA   Li N., Baycin-Hizal D., Latif H., Forster J., Betenbaugh M.J.,
RA   Famili I., Xu X., Wang J., Palsson B.O.;
RT   "Genomic landscapes of Chinese hamster ovary cell lines as revealed by
RT   the Cricetulus griseus draft genome.";
RL   Nat. Biotechnol. 31:759-765(2013).
//
RX   PubMed=26993211; DOI=10.1016/j.jbiotec.2016.03.022;
RA   Klanert G., Jadhav V., Shanmukam V., Diendorfer A.B., Karbiener M.,
RA   Scheideler M., Hernandez-Bort J.A., Grillari J., Hackl M., Borth N.;
RT   "A signature of 12 microRNAs is robustly associated with growth rate
RT   in a variety of CHO cell lines.";
RL   J. Biotechnol. 235:150-161(2016).
//
RX   PubMed=28876938; DOI=10.1021/acs.jproteome.7b00382;
RA   Heffner K.M., Baycin-Hizal D., Yerganian G., Kumar A., Can O.,
RA   O'Meally R.N., Cole R.N., Chaerkady R., Wu H., Bowen M.A.,
RA   Betenbaugh M.J.;
RT   "Lessons from the hamster: Cricetulus griseus tissue and CHO cell line
RT   proteome comparison.";
RL   J. Proteome Res. 16:3672-3687(2017).
//
RX   PubMed=32985598; DOI=10.1038/s41598-020-72959-8;
RA   Heffner K.M., Baycin-Hizal D., Majewska N.I., Kumar S., Dhara V.G.,
RA   Zhu J., Bowen M.A., Hatton D., Yerganian G., Yerganian A.,
RA   O'Meally R.N., Cole R.N., Betenbaugh M.J.;
RT   "Expanded Chinese hamster organ and cell line proteomics profiling
RT   reveals tissue-specific functionalities.";
RL   Sci. Rep. 10:15841-15841(2020).
//
RX   PubMed=34050613; DOI=10.1002/biot.202100165;
RA   Wurm M.J., Wurm F.M.;
RT   "Naming CHO cells for bio-manufacturing: genome plasticity and variant
RT   phenotypes of cell populations in bioreactors question the relevance
RT   of old names.";
RL   Biotechnol. J. 16:e2100165.1-e2100165.13(2021).
//
RX   PubMed=36610518; DOI=10.1016/j.ymben.2022.12.009;
RA   Kotidis P., Donini R., Arnsdorf J., Hansen A.H., Voldborg B.G.R.,
RA   Chiang A.W.T., Haslam S.M., Betenbaugh M.J., Jimenez del Val I.,
RA   Lewis N.E., Krambeck F.J., Kontoravdi C.;
RT   "CHOGlycoNET: comprehensive glycosylation reaction network for CHO
RT   cells.";
RL   Metab. Eng. 76:87-96(2023).
//