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Cellosaurus Rael (CVCL_7208)

[Text version]

Cell line name Rael
Synonyms Rael-BL; RAEL
Accession CVCL_7208
Resource Identification Initiative To cite this cell line use: Rael (RRID:CVCL_7208)
Comments Population: African; Kenyan.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_ZI17 (PUTRAL)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=4122458; DOI=10.1002/ijc.2910100108
Klein G., Dombos L., Gothoskar B.
Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus.
Int. J. Cancer 10:44-57(1972)

PubMed=4347031; DOI=10.1093/jnci/48.1.87
Hewetson J.F., Gothoskar B., Klein G.
Radioiodine-labeled antibody test for the detection of membrane antigens associated with Epstein-Barr virus.
J. Natl. Cancer Inst. 48:87-94(1972)

PubMed=4364259; DOI=10.1002/ijc.2910110210
Klein G., Dombos L.
Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome.
Int. J. Cancer 11:327-337(1973)

PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x
Povey S., Jeremiah S., Arthur E., Steel M., Klein G.
Differences in genetic stability between human cell lines from patients with and without lymphoreticular malignancy.
Ann. Hum. Genet. 44:119-133(1980)

PubMed=6811418; DOI=10.1016/S0171-2985(11)80031-8
Spira G., Koide N., Aman P., Ber R., Klein G.
Truncated mu chain in a Burkitt lymphoma line (P3HR-1) and its fate in various hemapoietic somatic cell hybrids.
Immunobiology 162:199-209(1982)

PubMed=6231253; DOI=10.1002/ijc.2910330407
Ehlin-Henriksson B., Klein G.
Distinction between Burkitt lymphoma subgroups by monoclonal antibodies: relationships between antigen expression and type of chromosomal translocation.
Int. J. Cancer 33:459-463(1984)

PubMed=3026973; DOI=10.1002/ijc.2910390215
Ehlin-Henriksson B., Manneborg-Sandlund A., Klein G.
Expression of B-cell-specific markers in different Burkitt lymphoma subgroups.
Int. J. Cancer 39:211-218(1987)

PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x
Siebert R., Willers C.P., Schramm A., Fossa A., Dresen I.M.G., Uppenkamp M., Nowrousian M.R., Seeber S., Opalka B.
Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines.
Br. J. Haematol. 91:350-354(1995)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=16051863; DOI=10.1128/JVI.79.16.10709-10717.2005
Kelly G.L., Milner A.E., Tierney R.J., Croom-Carter D.S.G., Altmann M., Hammerschmidt W., Bell A.I., Rickinson A.B.
Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A, -3B, and -3C expression in Burkitt's lymphoma cells and with increased resistance to apoptosis.
J. Virol. 79:10709-10717(2005)

PubMed=24590883; DOI=10.1002/gcc.22161
Maria Murga Penas E., Schilling G., Behrmann P., Klokow M., Vettorazzi E., Bokemeyer C., Dierlamm J.
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

PubMed=28960205; DOI=10.1038/cdd.2017.150
Fitzsimmons L., Boyce A.J., Wei W., Chang C., Croom-Carter D.S.G., Tierney R.J., Herold M.J., Bell A.I., Strasser A., Kelly G.L., Rowe M.
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Cell Death Differ. 25:241-254(2018)

Cross-references
Cell line collections NCBI_Iran; C186
Other Wikidata; Q54949130
Polymorphism and mutation databases Cosmic; 931109
Cosmic; 2361385
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number13