Cellosaurus A2780/100 (CVCL_7224)

Cell line name A2780/100
Synonyms A2780(100)
Accession CVCL_7224
Resource Identification Initiative To cite this cell line use: A2780/100 (RRID:CVCL_7224)
Comments Selected for resistance to: ChEBI; CHEBI:28830; Chlorambucil (CBL; Leukeran).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=10413308; DOI=10.1016/S0006-2952(99)00142-2
Horton J.K., Roy G., Piper J.T., Van Houten B., Awasthi Y.C., Mitra S., Alaoui-Jamali M.A., Boldogh I., Singhal S.S.
Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu.
Biochem. Pharmacol. 58:693-702(1999)

PubMed=10644989; DOI=10.1038/sj.onc.1203318
Roy G., Horton J.K., Roy R., Denning T., Mitra S., Boldogh I.
Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins.
Oncogene 19:141-150(2000)

Cross-references
Ontologies BTO; BTO:0003207