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Cellosaurus INS-1 832/13 (CVCL_7226)

[Text version]

Cell line name INS-1 832/13
Synonyms INS1 832/13; INS-1 (832/13); INS 832/13 ; 832/13; 832/13 INS-1
Accession CVCL_7226
Resource Identification Initiative To cite this cell line use: INS-1 832/13 (RRID:CVCL_7226)
Comments Characteristics: Shows robust glucose-stimulated insulin secretion (GSIS) (Millipore).
Transfected with: HGNC; 6081; INS.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCIt; C17262; X-Ray.
Misspelling: INS-1 823/13; Occasionally.
Misspelling: 823/13; Occasionally.
Derived from sampling site: Pancreas; islets of Langerhans.
Disease Rat insulinoma (NCIt: C121566)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH.
Hierarchy Parent: CVCL_0352 (INS-1)
Sex of cell Male
Age at sampling 666D
Category Cancer cell line

PubMed=10868964; DOI=10.2337/diabetes.49.3.424
Hohmeier H.E., Mulder H., Chen G.-X., Henkel-Rieger R., Prentki M., Newgard C.B.
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.
Diabetes 49:424-430(2000)

PubMed=18755687; DOI=10.1074/jbc.M804665200
Ronnebaum S.M., Jensen M.V., Hohmeier H.E., Burgess S.C., Zhou Y.-P., Qian S., MacNeil D., Howard A., Thornberry N., Ilkayeva O., Lu D.-H., Sherry A.D., Newgard C.B.
Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets.
J. Biol. Chem. 283:28909-28917(2008)

PubMed=23555872; DOI=10.1371/journal.pone.0060030
Hectors T.L.M., Vanparys C., Pereira-Fernandes A., Martens G.A., Blust R.
Evaluation of the INS-1 832/13 cell line as a beta-cell based screening system to assess pollutant effects on beta-cell function.
PLoS ONE 8:E60030-E60030(2013)

Cell line collections AddexBio; C0018024/5026
Millipore; SCC207
Cell line databases/resources Lonza; 11
TOKU-E; 4125
Ontologies BCGO; BCGO_0000115
BTO; BTO:0003318
Metabolomic databases MetaboLights; MTBLS951
Other Wikidata; Q54897743
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number17